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Clinical studies show an average of 15% body weight loss over 68 weeks with semaglutide, and up to 2022% with tirzepatide

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A distinct feature of these proteins is their structural fold, which includes -helices surrounding a -barrel structure and an overlapping -strand motif

The STEP trials demonstrated that patients receiving semaglutide lost between 5% and 22% of their body weight depending on dose, with many maintaining this loss for over a year